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5 Day Workout Plan for Muscle Gain & Strength (Trainer Approved & Science-Backed)

The most effective 5 day workout plan for building strength and muscle gain is based on progressive overload, optimal exercise selection, and the latest exercise science. This guide gives you everything you need—step-by-step routines, key muscle-building strategies, and answers to common gym questions.

Building muscle requires a smart, structured plan that targets all major muscle groups, balances training volume and recovery, and prioritizes consistent progression. Whether you’re a beginner or an experienced lifter, this 5-day split will help you gain muscle and strength efficiently, backed by current research and expert recommendations.

  • Train each muscle group at least twice weekly
  • Focus on compound lifts with targeted isolation movements
  • Gradually increase weights or reps (progressive overload)
  • Prioritize sleep, recovery, and proper nutrition
  • Adjust exercises as needed for your experience level

For official training standards and safety tips, visit the CDC’s Strength Training Basics and ACSM’s Physical Activity Guidelines.

Why a 5 Day Workout Plan Works for Muscle Gain

A 5 day workout split lets you hit each muscle group with the right frequency and volume for optimal hypertrophy and strength. Multiple studies confirm that training each muscle group twice a week, with 10–20 sets weekly, delivers superior results compared to once-a-week splits.

  • Maximizes training volume and intensity
  • Enables recovery for muscle growth
  • Perfect for intermediate and advanced lifters
  • Easily adjustable for beginners

For a deep dive, check out GQ’s science-based muscle-building guide.

Core Principles for Strength and Muscle Gain

1. Progressive Overload

Gradually increase your weights, reps, or sets week-to-week. Progressive overload is proven to stimulate muscle adaptation and growth (NSCA, 2024).

2. Training Volume & Frequency

  • Aim for 10–20 total sets per muscle group per week
  • Train each muscle group at least twice weekly
  • Use compound lifts for major strength gains, isolation moves for detail

3. Recovery

  • Get 7–9 hours of sleep per night
  • Allow at least 48 hours between working the same muscle group
  • Schedule one active recovery day per week

4. Nutrition

  • Protein: 1.6–2.2g per kg of bodyweight
  • Caloric surplus required for muscle gain (TDEE calculator)
  • Hydrate well (at least 3L/day)

Detailed 5 Day Workout Plan

Day 1 – Upper Body: Chest, Back, Arms

ExerciseSetsRepsNotes
Barbell Bench Press46–8Heavy, full range of motion
Pull-Ups (or Lat Pulldown)38–10Add weight as you get stronger
Dumbbell Chest Fly310–12Slow eccentric, big stretch
Seated Cable Row310–12Squeeze shoulder blades
Triceps Rope Pressdown310–15Keep elbows tucked
EZ Bar Curl310–12Full stretch at bottom

Day 2 – Lower Body: Quads, Glutes, Hamstrings, Calves

ExerciseSetsRepsNotes
Barbell Squat48–10Depth: thighs at least parallel
Walking Lunges310/legAlternate legs, dumbbells optional
Romanian Deadlift38–10Focus on hamstring stretch
Leg Press310–12Feet hip-width, slow lower
Seated Calf Raise312–15Pause at top, slow negative
Hanging Knee Raise312–15Control your movement

Day 3 – Upper Body Pull: Back, Biceps

ExerciseSetsRepsNotes
Pull-Ups or Lat Pulldowns46–8Add weight or slow tempo for more challenge
Barbell Bent Over Row38–10Keep back flat, squeeze at top
Seated Cable Row310–12Control the movement, full stretch
Face Pulls312–15Rope at eyebrow level, pull apart
Dumbbell Biceps Curl310–12Squeeze at top, avoid swinging

Day 4 – Upper Body: Shoulders, Back, Arms

ExerciseSetsRepsNotes
Standing Overhead Press48–10Brace core, don’t arch back
Lat Pulldown310–12Pull to upper chest
Arnold Dumbbell Press310–12Rotate for full range
Face Pull312–15Rope at eyebrow level
Dumbbell Hammer Curl310–12Neutral grip, squeeze at top
Overhead Triceps Extension310–12Use cable or dumbbell

Day 5 – Lower Body: Glutes, Hamstrings, Calves, Core

ExerciseSetsRepsNotes
Deadlift36–8Focus on form, keep back flat
Bulgarian Split Squat38/legRear foot on bench, slow descent
Lying Leg Curl310–12Squeeze glutes/hamstrings
Standing Calf Raise312–15Go all the way up & down
Glute Bridge312–15Pause at top, squeeze glutes
Plank345 secTight core, straight line

Additional Tips for Maximum Results

  • Warm up with 5–10 minutes of light cardio and dynamic stretches
  • Rest 60–120 seconds between compound sets; 45–60 seconds for isolation/core
  • Track your progress: Use a workout app or journal
  • Adjust weights weekly to keep making progress
  • Include one active recovery day (light cardio, stretching, or yoga)

FAQ: 5 Day Muscle Gain Plan

Q: Can beginners use this plan?
A: Yes! Start with lighter weights, use perfect form, and reduce sets as needed.

Q: How fast will I see results?
A: Strength gains show in 3–5 weeks; visible muscle gain often in 6–12 weeks (Health.com, 2024).

Q: Can I swap exercises?
A: Yes! Substitute similar movements if you don’t have access to specific equipment.

Conclusion

A 5 day workout plan for strength and muscle gain delivers proven results when you follow the science and stay consistent. Use this routine, prioritize sleep and nutrition, and update your plan as you get stronger. You’ll see results, boost your confidence, and build a healthier body.


Written by

Josette Henley

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